Cyclohexanethiol → HCID 14650546, compound

HRID 1886442Notes

Reaction equation

HRID 1886442 reaction equation
[C:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[O:9][C:8]([CH3:14])([CH3:13])[CH:7]1[O:15][CH:6]21)#[N:2].[CH:16]1([SH:22])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1.[OH-].C([N+](C)(C)C)C1C=CC=CC=1>O1CCCC1>[C:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[O:9][C:8]([CH3:14])([CH3:13])[C@@H:7]([OH:15])[C@@H:6]2[S:22][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)#[N:2]

Participants

5

Reactant 3

HCID 15290CyclohexanethiolHCID 66854Benzyltrimethylammonium hydroxideHCID 108673602,2-Dimethyl-3,4-epoxy-6-cyanochroman

Product 1

HCID 14650546HCID 14650546, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A mixture of 1.5 g of 6-cyano-2,2-dimethyl-3,4-epoxychroman, 1.2 g of cyclohexylmercaptan and 0.3 g of a 35% methanolic solution of benzyltrimethylammonium hydroxide in 10 ml of tetrahydrofuran is refluxed for 8 hours.

Workup

  1. temperatureis refluxed for 8 hours

Sources & evidence

ORD record
ord-f5726e81eab0428794033f632cf2df7a
Source dataset
uspto-grants-1992_09
Patent number
US05151442

Reaction notes

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