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HRID 1886770作成日:2026年10月26日

1-(2-Chlorophenyl)-2-(1-tetrazolyl)ethanone → alpha-(2-Chlorophenyl)-2H-tetrazole-2-ethanol, (alphaR)-

https://huagongshe.com/reaction/1886770

反応式

関与物質

役割名称HCID仕込み量
反応物1-(2-Chlorophenyl)-2-(1-tetrazolyl)ethanoneHCID 52914739—
反応物1-(2-Chlorophenyl)-2-(2H-tetrazol-2-yl)ethanoneHCID 67120091—
生成物alpha-(2-Chlorophenyl)-2H-tetrazole-2-ethanol, (alphaR)-HCID 67120090—

反応手順

The same procedure as in Preparation Example 3 was repeated, with the exception that 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-one, prepared in Preparation Example 2, was used instead of 1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-1-yl)ethan-1-one, to afford (R)-1-(2-chlorophenyl)-2-(1,2,3,4-tetrazol-2-yl)ethan-1-ol (hereinafter referred to as “2N alcohol”). The conversion rate and optical purity of the product are given in Table 1, below.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08501436B2
出典データセットuspto-grants-2013_08
ORD IDord-1ebcb65b71f84c4b8ee1ed306232cb28
出典メモuspto-grants-2013_08