Picolinic acid → HCID 44160106, compound

Participants

Role	Name	HCID	Charge
Reactant	Picolinic acid	HCID 1018	—
Reactant	2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid	HCID 18988374	—
Reactant	(+/-) 9-Amino-2-pyridin-4-yl-5,6,8,9-tetrahydro-7-oxa-1,4a-diaza-benzocyclohepten-4-one	HCID 66846193	—
Product	HCID 44160106	HCID 44160106	—

Reaction Steps

By analogy with the method described in example 1 (step 1.4), using (+/−) 9-amino-2-pyridin-4-yl-5,6,8,9-tetrahydro-7-oxa-1,4-a-diaza-benzocyclohepten-4-one and 2-pyridine carboxylic acid in place of (+/−)-9-amino-2-pyrimidin-4-yl-5,6,8,9-tetrahydro-7-oxa-1,4-a-diaza-benzocyclohepten-4-one and 3,4-dihydro-1H-isoquinoline-2,7-dicarboxylic acid 2-tert-butyl ester, the compound, 0.035 g (57%), was obtained as a white powder.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08501728B2
Source dataset	uspto-grants-2013_08
ORD ID	ord-444fd4050cd14a2294470e79c2ebdccb
Source note	uspto-grants-2013_08