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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887095Generated: November 1, 2026

7-Chloro-6-fluoroisoquinoline → 7-Chloro-6-(piperidin-4-yloxy)-isoquinoline-hydrochloride

https://huagongshe.com/reaction/1887095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Chloro-6-fluoroisoquinolineHCID 53418922—
Reactant6-(Piperidin-4-yloxy)-isoquinoline hydrochlorideHCID 67428966—
Product7-Chloro-6-(piperidin-4-yloxy)-isoquinoline-hydrochlorideHCID 67432537—

Reaction Steps

Starting from 7-Chloro-6-fluoro-isoquinoline (150), the title compound was prepared by the same synthetic route as for compound 124. Rt=0.66 min (Method #1), detected mass: 263.1/265.1 (M+H+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501736B2
Source datasetuspto-grants-2013_08
ORD IDord-b7873a3d63494558a14efc1a9476d70c
Source noteuspto-grants-2013_08