反应详情

Method A was applied to a mixture of 2-chloro-4-iodo-5-(trifluoromethyl)pyridine (45 mg, 0.15 mmol), 2-aminopyridine (28 mg, 0.30 mmol), Pd2(dba)3 (12 mg, 0.013 mmol), xantphos (8 mg, 0.014 mmol) and cesium carbonate (108 mg, 0.33 mmol) in dioxane (2.5 ml).