Iodoethane → HCID 59620388, compound

HRID 1887732Notes

Reaction equation

[C:1]([O:5][C:6]([NH:8][C@@H:9]([C:20]([OH:22])=[O:21])[CH2:10][C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[NH:13][CH:12]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:23](I)[CH3:24]>>[C:1]([O:5][C:6]([NH:8][C@H:9]([CH2:10][C:11]1[C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[N:13]([CH2:23][CH3:24])[CH:12]=1)[C:20]([OH:22])=[O:21])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 6340Iodoethane

HCID 111050N-((tert-Butoxy)carbonyl)-D-tryptophan

Product 1

HCID 59620388HCID 59620388, compound

Procedure

The procedure of Referential Example 1(a) was repeated, except that N-tert-butoxycarbonyl-D-tryptophan (462 mg) and ethyl iodide (184 μL) were used, whereby the title compound (456 mg) was yielded.

Sources & evidence

ORD record: ord-ba66e742250a40579c67ac63d798f706
Source dataset: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08501772B2

Reaction notes

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