Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887841Generated: October 25, 2026

1-Methyl-1H-pyrazole-4-carboxylic acid → Methyl-1H-pyrazole-4-carboxylic acid (2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridin-3-ylmethyl)-amide

https://huagongshe.com/reaction/1887841

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-pyrazole-4-carboxylic acidHCID 643160—
Reactant3-(aminomethyl)-2-(oxazol-2-yl)-1-phenyl-1,8-naphthyridin-4(1H)-oneHCID 71208505—
ProductMethyl-1H-pyrazole-4-carboxylic acid (2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridin-3-ylmethyl)-amideHCID 71217335—

Reaction Steps

Methyl-1H-pyrazole-4-carboxylic acid (2-oxazol-2-yl-4-oxo-1-phenyl-1,4-dihydro-[1,8]naphthyridin-3-ylmethyl)-amide was prepared starting from intermediate B and 1-methyl-1H-pyrazole-4-carboxylic acid. MS calcd. for C23H19N6O3 [(M+H)+] 427.1, obsd. 427.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-4a596aa3687f4ee49381c129df1f9aef
Source noteuspto-grants-2013_08