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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887860Generated: October 25, 2026

6-Methoxynicotinic acid → N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-methoxy-nicotinamide

https://huagongshe.com/reaction/1887860

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxynicotinic acidHCID 592499—
Reactant3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-oneHCID 71208398—
ProductN-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-methoxy-nicotinamideHCID 71208877—

Reaction Steps

N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-methoxy-nicotinamide was prepared starting from intermediate D and 6-methoxy-nicotinic acid. MS calcd. for C23H18ClN3O3 [(M+H)+] 419.1, obsd. 420 [(M+H)+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-c860ab8b20644e17997db8aa8937ee75
Source noteuspto-grants-2013_08