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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887866Generated: October 29, 2026

2-Dimethylamino-isonicotinic acid → N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-dimethylamino-iso-nicotinamide

https://huagongshe.com/reaction/1887866

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Dimethylamino-isonicotinic acidHCID 6484234—
Reactant3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-oneHCID 71208398—
ProductN-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-dimethylamino-iso-nicotinamideHCID 71208316—

Reaction Steps

N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-2-dimethylamino-iso-nicotinamide was prepared starting from intermediate D and 2-dimethylamino-isonicotinic acid. MS calcd. for C24H22ClN4O2 [(M+H)+] 433.1, obsd. 432.9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-69035be51b924d2680e742dabc30400b
Source noteuspto-grants-2013_08