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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1887872Generated: October 25, 2026

4-(1,3-Oxazol-5-yl)benzoic Acid → N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-4-oxazol-5-yl-benzamide

https://huagongshe.com/reaction/1887872

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1,3-Oxazol-5-yl)benzoic AcidHCID 2776414—
Reactant3-(aminomethyl)-7-chloro-1-phenylquinolin-4(1H)-oneHCID 71208398—
ProductN-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-4-oxazol-5-yl-benzamideHCID 71208268—

Reaction Steps

N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-4-oxazol-5-yl-benzamide was prepared starting from intermediate D and 4-oxazol-5-yl-benzoic acid. MS calcd. for C26H18ClN3O3 [(M+H)+] 455.9, obsd. 456.0.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501732B2
Source datasetuspto-grants-2013_08
ORD IDord-0a306238b4a341febc6b9d8187a4ef13
Source noteuspto-grants-2013_08