4-Piperidineethanol → HCID 71217355, compound

Participants

Reaction Steps

4-(2-Hydroxy-ethyl)-3,4,5,6-tetrahydro-2H-[1,2′]bipyridinyl-5′-carboxylic acid (7-chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-amide was prepared starting from intermediate E and 4-(hydroxyethyl)piperidine. 1H NMR (400 MHz, DMSO-d6) δ ppm 8.50 (d, J=2.01 Hz, 1H) 8.43 (t, J=5.65 Hz, 1H) 8.21 (d, J=9.04 Hz, 1H) 7.80-7.88 (m, 2H) 7.54-7.65 (m, 3H) 7.49-7.53 (m, 2H) 7.38 (dd, J=8.66, 1.88 Hz, 1H) 6.84 (d, J=2.00 Hz, 1H) 6.72 (d, J=8.78 Hz, 1H) 4.25-4.33 (m, 5H) 3.38 (q, J=6.10 Hz, 2H) 2.75 (t, J=12.50 Hz, 2H) 1.58-1.67 (m, 3H) 1.28 (q, J=6.53 Hz, 2H) 0.92-1.05 (m, 2H).

Provenance & Evidence