2-Methoxyethylamine → HCID 71208256, compound

HRID 1887893Notes

Reaction equation

HRID 1887893 reaction equation
Cl[C:2]1[CH:29]=[CH:28][C:5]([C:6]([NH:8][CH2:9][C:10]2[C:19](=[O:20])[C:18]3[C:13](=[CH:14][C:15]([Cl:21])=[CH:16][CH:17]=3)[N:12]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH:11]=2)=[O:7])=[CH:4][N:3]=1.[CH3:30][O:31][CH2:32][CH2:33][NH2:34]>>[Cl:21][C:15]1[CH:14]=[C:13]2[C:18]([C:19](=[O:20])[C:10]([CH2:9][NH:8][C:6](=[O:7])[C:5]3[CH:28]=[CH:29][C:2]([NH:34][CH2:33][CH2:32][O:31][CH3:30])=[N:3][CH:4]=3)=[CH:11][N:12]2[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 714870636-chloro-N-((7-chloro-4-oxo-1-phenyl-1,4-dihydroquinolin-3-yl)methyl)nicotinamide

Product 1

HCID 71208256HCID 71208256, compound

Procedure

N-(7-Chloro-4-oxo-1-phenyl-1,4-dihydro-quinolin-3-ylmethyl)-6-(2-methoxy-ethyl-amino)-nicotinamide was prepared starting from intermediate E and 2-methoxyethylamine. MS calcd. for C25H23ClN4O3 [(M+H)+] 463.2, obsd. 463.0.

Sources & evidence

ORD record
ord-7a5832b3d4ce4872b3cf567d64482a58
Source dataset
uspto-grants-2013_08
Patent number
US08501732B2

Reaction notes

Loading…