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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1888068Generated: November 1, 2026

Malic Acid → HCID 86648417, compound

https://huagongshe.com/reaction/1888068

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMalic AcidHCID 525—
ReactantDonepezilHCID 3152—
SolventEthanolHCID 702—
SolventEthyl AcetateHCID 8857—
ProductHCID 86648417HCID 86648417—

Reaction Steps

1.901 g of Donepezil is dissolved in 15 ml of ethyl acetate. A solution (4 ml) of malic acid (0.679 g) in absolute ethanol is added slowly and drop-wisely and the resulted solution is stirred. The solid precipitated is filtered with suction to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08501779B2
Source datasetuspto-grants-2013_08
ORD IDord-714632594a5f453690dc684c51d0e3ad
Source noteuspto-grants-2013_08