反应详情

温度

0 °C

The product from Example 28A (300 mg, 0.85 mmol) in CH2Cl2 (10 mL) containing triethylamine (257 mg, 2.54 mmol) was treated with methanesulfonyl chloride (145 mg, 1.27 mmol) at 0° C. The mixture was stirred for 30 min at 0° C., diluted with water and extracted with CH2Cl2 (2×). The combined organic layers were dried over MgSO4, filtered and concentrated to afford the title compound.

1. extractionextracted with CH2Cl2 (2×)
2. dry with materialThe combined organic layers were dried over MgSO4
3. filtrationfiltered
4. concentrationconcentrated