HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 58047222, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 58047460 | HCID 58047460 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 58047222 | HCID 58047222 | 30% |
Reaction Steps
Using methyl 5-[(1-{5-[(4-ethoxybenzyl)oxy]-1-benzofuran-2-yl}ethyl)amino]-5-oxopentanoate (214 mg, 0.489 mmol) obtained in Example 97, methanol (2.0 mL) and 8N aqueous sodium hydroxide solution (0.10 mL, 0.82 mmol), an operation in the same manner as in Example 35 was performed to give the title compound (10.2 mg, yield 30%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501804B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-779021ee977749778e2fc410919e35e2 |
| Source note | uspto-grants-2013_08 |