Hydrochloric Acid → 4-(8-Oxo-6-thioxo-5-(4-methylphenyl)-5,7-diazaspiro[3.4]oct-7-yl)-2-trifluoromethylbenzonitrile
Reaction equation
[CH3:30][OH:31].[ClH:33].[NH:1]=[C:2]1[N:3]([c:18]2[cH:19][c:20]([C:26]([F:27])([F:28])[F:29])[c:21]([C:22]#[N:23])[cH:24][cH:25]2)[C:4](=[S:17])[N:5]([c:10]2[cH:11][cH:12][c:13]([CH3:16])[cH:14][cH:15]2)[C:6]12[CH2:7][CH2:8][CH2:9]2.[OH2:32]>>[C:2]1(=[O:31])[N:3]([c:18]2[cH:19][c:20]([C:26]([F:27])([F:28])[F:29])[c:21]([C:22]#[N:23])[cH:24][cH:25]2)[C:4](=[S:17])[N:5]([c:10]2[cH:11][cH:12][c:13]([CH3:16])[cH:14][cH:15]2)[C:6]12[CH2:7][CH2:8][CH2:9]2Participants
5
Sources & evidence
- ORD record
- ord-6f11a4e07d2d4e46b21c949eb458b9ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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