Hydrazine hydrate (1:1) → 1,2,4-Thiadiazole-5-carbohydrazide

HRID 1889025Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1889025
[S:1]1[C:5]([C:6]([O:8]CC)=O)=[N:4][CH:3]=[N:2]1.O.[NH2:12][NH2:13]>>[S:1]1[C:5]([C:6]([NH:12][NH2:13])=[O:8])=[N:4][CH:3]=[N:2]1

Komponenten

3

Edukt 2

HCID 24654Hydrazine hydrate (1:1)HCID 54278093Ethyl 1,2,4-thiadiazole-5-carboxylate

Produkt 1

HCID 679706231,2,4-Thiadiazole-5-carbohydrazide

Versuchsvorschrift

Ethyl 1,2,4-thiadiazole-5-carboxylate (I79) (246 mg, 1.555 mmol) and hydrazine hydrate (0.151 mL, 3.11 mmol) were heated at 80° C. for 5 hr. The solvents were removed in vacuo to afford a yellow solid in 173 mg.

Aufarbeitung

  1. customThe solvents were removed in vacuo
  2. customto afford a yellow solid in 173 mg

Quellen und Nachweise

ORD-Eintrag
ord-b8640288e2f145ad8816a2e4a2e9a250
Quelldatensatz
uspto-grants-2013_08
Patentnummer
US08501946B2

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