Lithium Hydroxide → HCID 59610055, compound

Participants

Reaction Steps

The compound of example B29 was obtained by similar method described in example B28 using 4-{2-[2-(4-Cyclopropanesulfonyl-phenyl)-2-(2,4-difluoro-phenoxy)-acetylamino]-thiazol-5-yloxy}-benzoic acid methyl ester (0.17 g, 0.29 mmol), LiOH (0.062 g, 1.48 mmol) in THF: MeOH: Water (1:1:1, 9 mL) to provide the title compound (0.117 g, 72%).

Provenance & Evidence