Lithium Hydroxide → HCID 56592348, compound

Participants

Reaction Steps

The compound of example B30 was obtained by similar method described in example B28 using 4-(2-{2-(4-Cyclopropanesulfonyl-phenyl)-2-[(R)-(tetrahydro-furan-3-yl)oxy]-acetylamino}-thiazol-5-yloxy)-benzoic acid methyl ester (0.180 g, 0.32mmol), LiOH (0.067 g, 1.61 mmol) in THF: MeOH: Water (1:1:1, 9 mL) to provide the title compound (0.160 mg, 92%).

Provenance & Evidence