HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59351564, compound → HCID 59351494, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59351564 | HCID 59351564 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Tetrahydrofurfuryl alcohol | HCID 7360 | — |
| Product | HCID 59351494 | HCID 59351494 | 78% |
Reaction Steps
To a solution (20 mL) of 3-(2-phenylethyl)-6-vinylquinazoline-2,4(1H,3H)-dione (0.6 g) in tetrahydrofuran-methanol (1:1) was added palladium carbon (10%, 0.06 g), and the mixture was stirred under hydrogen atmosphere for 4 hr. Insoluble material was filtered off, and the filtrate was concentrated to give the title compound as a brown solid (0.47 g, 78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08501750B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-96f698878ed341e287926045708611b4 |
| Source note | uspto-grants-2013_08 |