Sodium Hydroxide → Ethanol, 2-(1-phenylhydrazino)-

Participants

Reaction Steps

A solution of acetyl-2-(2-hydroxyethyl)-2-phenylhydrazine (i) (0.5 g, 2.57 mmol) in 6N hydrogen chloride 5 ml was refluxed for 2 hours. The reaction was cooled to room temperature and basified with 6N sodium hydroxide to PH 8. The solution was extracted with DCM 2×50 ml, washed with brine 2×30 ml. The organic was dried (MgSO4) and removed in vacuo. The residue was used to next step without further purification.

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