(4-Methoxyphenyl)boronic acid → HCID 178492022, compound

HRID 1890342Notes

Reaction equation

HRID 1890342 reaction equation
C([O:8][C:9]1[N:14]=[C:13]2[NH:15][CH:16]=[N:17][C:12]2=[CH:11][CH:10]=1)C1C=CC=CC=1.[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1>>[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([N:15]2[C:13]3=[N:14][C:9]([OH:8])=[CH:10][CH:11]=[C:12]3[N:17]=[CH:16]2)=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 178420377HCID 178420377, compound

Product 1

HCID 178492022HCID 178492022, compound

Procedure

From 5-(benzyloxy)-3H-imidazo[4,5-b]pyridine and 4-methoxyphenylboronic acid, prepared in a similar manner as the one described in Example 1.25, Steps A and B, the title compound was obtained as a white solid. 1H NMR (400 MHz, methanol-d4) δ ppm 3.9 (s, 3H), 6.92 (d, J=8.8 Hz, 1H), 7.16 (d, J=8.8 Hz, 2H), 7.73 (d, J=8.8 Hz, 2H), 8.10 (d, J=8.8 Hz, 1H), 9.20 (s, 1H).

Sources & evidence

ORD record
ord-9b3f7cc99cd141f4977de6e922c4ec98
Source dataset
uspto-grants-2013_08
Patent number
US08507473B2

Reaction notes

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