反应详情

温度

140 °C

2,6-Dichloro-3-nitropyridine (5 g, 25.9 mmol) and cyclohexanamine (5.14 g, 51.8 mmol) were added to ethanol (17.5 mL). The reaction mixture was heated at 140° C. by microwave irradiation for 3 h. A yellow solid precipitated out. The solid was filtered, washed with cold ethanol, and dried under vacuum to afford the title compound (2.162 g) without further purification. LCMS m/z=256.40 [M+H]+.

1. customA yellow solid precipitated out
2. filtrationThe solid was filtered
3. washwashed with cold ethanol
4. customdried under vacuum