Phosphorus oxychloride → HCID 178515750, compound

Participants

Reaction Steps

From 3-(2-bromophenyl)-2-hydroxy-3H-imidazo[4,5-b]pyridin-5-yl methanesulfonate and POCl3, prepared in a similar manner as the one described in Example 1.136, the title compound was obtained. LCMS m/z=323.90 [M+H]+, 1H NMR (400 MHz, methanol-d4) δ ppm 6.72 (d, J=8.6 Hz, 1H), 7.57-7.65 (m, 3H), 7.90 (dd, J1=8.1 Hz, J2=1.2 Hz, 1H), 7.93 (d, J=8.6 Hz, 1H).

Provenance & Evidence