HuagongsheHuagongshe Chemistry Print Report · For research reference only
Picolinic acid → HCID 44159005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Picolinic acid | HCID 1018 | — |
| Reactant | 2-((Tert-butoxy)carbonyl)-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid | HCID 18988374 | — |
| Reactant | HCID 66841894 | HCID 66841894 | — |
| Product | HCID 44159005 | HCID 44159005 | — |
Reaction Steps
By analogy with the method described in example 1 (step 1.5), using 9-amino-4-oxo-2-pyridin-4-yl-5,6,8,9-tetrahydro-4H-1,4a,7-triaza-benzocycloheptene-7-carboxylic acid ethyl ester and 3,4-dihydro-1H-isoquinoline-2,7-dicarboxylic acid 2-tert-butyl ester in place of (+/−)-9-amino-4-oxo-2-pyrimidin-4-yl-5,6,8,9-tetrahydro-4H-1,4a,7-triaza benzocycloheptene-7-carboxylic acid ethyl ester hydrobromide (1:1) and 2-pyridine carboxylic acid, the compound, 0.286 g (80%), was obtained as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507475B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-b71e17458f2246b896268e150b74ee5a |
| Source note | uspto-grants-2013_08 |