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HRID1890438

反应详情

EQUATION

反应方程式

HRID 1890438 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc2c(c1)NC(=O)CC2
HCID12899418

7-Methoxy-3,4-dihydroquinolin-2(1H)-one

C10H11NO2

结构：CC(C)(C)OC(=O)N1CC(COS(C)(=O)=O)C1
HCID21959416

tert-Butyl 3-{[(methanesulfonyl)oxy]methyl}azetidine-1-carboxylate

C10H19NO5S

PRODUCTS

生成物

1
结构：COc1ccc2c(c1)N(CC1CN(C(=O)OC(C)(C)C)C1)C(=O)CC2
HCID67130905

未命名化合物

收率 71%

PROCEDURE

实验过程

Using the procedure of Example 2, step 2.i, but starting from 3,4-dihydro-7-methoxy-2(1H)-quinolinone (prepared according to WO 2006/134378; 886 mg) and 3-[[(methylsulfonyl)oxy]methyl]-1-azetidinecarboxylic acid tert-butyl ester (1459 mg; prepared according to WO 02/066470), the title compound was isolated as a colourless oil (1223 mg; 71% yield).