3-(azidomethyl)-1H-pyrrolo[2,3-b]pyridine → (1H-pyrrolo[2,3-b]pyridin-3-yl)methanamine

Participants

Reaction Steps

To a mixture of 3-(azidomethyl)-1H-pyrrolo[2,3-b]pyridine (A-4) (1.50 g, 8.63 mmol) in EtOAc (150 mL) was added 10% Pd/C (1.10 g). The resulting reaction mixture was stirred under one atmosphere of H2 at room temperature for 3 h. The mixture was filtered, and the filtrate was concentrated to afford the title compound (1.15 g).

Provenance & Evidence