反应详情

To a suspension of 3-chloro-6-methyl-pyridazine (3 g, 23.3 mmol) in ethanol (45 mL) was added hydrazine hydrate (45 mL) and the resultant mixture was heated to reflux for 3 hrs. Most of the solvent was removed under reduced pressure and the white solid was collected by filtration and washed with ethanol. Upon drying 2.3 g of (6-methyl-pyridazin-3-yl)-hydrazine was obtained as a white crystalline solid (80% yield).

1. temperatureto reflux for 3 hrs
2. customMost of the solvent was removed under reduced pressure
3. filtrationthe white solid was collected by filtration
4. washwashed with ethanol
5. dry with materialUpon drying 2.3 g of (6-methyl-pyridazin-3-yl)-hydrazine