HCID 58550503, compound → HCID 16775514, compound

Participants

Reaction Steps

Propane-1-sulfonic acid (2-methyl-5-nitro-phenyl)-amide (10 g, 39 mmol) was hydrogenated over Raney nickel (1.0 g) in methanol at 50° C. and 70 psi for 4 h. Then, the catalyst was filtered out, washed with warm methanol, and the combined filtrates were evaporated to give 8.0 g (90%) of propane-1-sulfonic acid (5-amino-2-methyl-phenyl)-amide as colorless solid.

Provenance & Evidence