Hydrochloric Acid → {3-[2-(2,4-Difluorophenyl)-3-methylimidazo[1,2-alpha]pyridin-6-yl]phenyl}methanol hydrochloride

Participants

Reaction Steps

A solution of 130 mg of {3-[2-(2,4-difluorophenyl)-3-methylimidazo[1,2-α]pyridin-6-yl]phenyl}methanol in dichloromethane and methanol is passed through a frit and 3.7 ml of a 0.1N solution of hydrochloric acid in isopropanol are added to the filtrate. The reaction mixture is then concentrated under reduced pressure. The residue obtained is triturated from diethyl ether and recovered by filtration and then oven-dried under reduced pressure. 128 mg of compound are obtained.

Provenance & Evidence