反应详情

A solution of 130 mg of {3-[2-(2,4-difluorophenyl)-3-methylimidazo[1,2-α]pyridin-6-yl]phenyl}methanol in dichloromethane and methanol is passed through a frit and 3.7 ml of a 0.1N solution of hydrochloric acid in isopropanol are added to the filtrate. The reaction mixture is then concentrated under reduced pressure. The residue obtained is triturated from diethyl ether and recovered by filtration and then oven-dried under reduced pressure. 128 mg of compound are obtained.

1. additionare added to the filtrate
2. concentrationThe reaction mixture is then concentrated under reduced pressure
3. customThe residue obtained
4. customis triturated from diethyl ether
5. filtrationrecovered by filtration
6. customoven-dried under reduced pressure