反应详情

Benzaldehyde (21.2 g; 0.2 mol) was added, dropwise, to a solution of 3-aminopiperidine (20 g; 0.2 mol) in toluene (80 ml). The solution thus obtained was stirred at room temperature, After 3 h the solvent was removed by evaporation at reduced pressure and the residue was taken up twice with toluene. 29 g N-(phenylmethylene)piperidine-3-amine was thus obtained, and was used in the subsequent reactions without further purification.

1. customThe solution thus obtained
2. customwas removed by evaporation at reduced pressure