Formaldehyde → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(8-methyloctahydro-2H-pyrazino[1,2-a]pyrazin-2-yl)-3-pyridinyl]-N,2-dimethylpropanamide
Reaction equation
[C:48]([O:49][BH-:50]([O:51][C:52](=[O:53])[CH3:54])[O:55][C:56](=[O:57])[CH3:58])(=[O:59])[CH3:60].[CH2:46]=[O:47].[CH3:62][C:63]#[N:64].[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([CH3:17])[c:18]2[cH:19][n:20][c:21]([N:32]3[CH2:33][CH:34]4[N:35]([CH2:36][CH2:37]3)[CH2:38][CH2:39][NH:40][CH2:41]4)[cH:22][c:23]2-[c:24]2[c:25]([CH3:31])[cH:26][c:27]([F:30])[cH:28][cH:29]2)([CH3:42])[CH3:43])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:44])[F:45].[Na+:61]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([CH3:17])[c:18]2[cH:19][n:20][c:21]([N:32]3[CH2:33][CH:34]4[N:35]([CH2:36][CH2:37]3)[CH2:38][CH2:39][N:40]([CH3:48])[CH2:41]4)[cH:22][c:23]2-[c:24]2[c:25]([CH3:31])[cH:26][c:27]([F:30])[cH:28][cH:29]2)([CH3:42])[CH3:43])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:44])[F:45]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-de68df9420224a10bc2a476204700e3f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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