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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 189164Generated: October 30, 2026

Formaldehyde → 2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(8-methyloctahydro-2H-pyrazino[1,2-a]pyrazin-2-yl)-3-pyridinyl]-N,2-dimethylpropanamide

https://huagongshe.com/reaction/189164

Reaction equation

Participants

RoleNameHCIDCharge
ReactantFormaldehydeHCID 712—
ReactantSodium ionHCID 923—
ReactantAcetonitrileHCID 6342—
ReactantTriacetoxyborohydrideHCID 2724942—
Reactant2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methyl phenyl)-6-(octahydro-2H-pyrazino[1,2-a]pyrazin-2-yl)-3-pyridinyl]-N,2-dimethylpropanamideHCID 59215771—
Product2-[3,5-bis(trifluoromethyl)phenyl]-N-[4-(4-fluoro-2-methylphenyl)-6-(8-methyloctahydro-2H-pyrazino[1,2-a]pyrazin-2-yl)-3-pyridinyl]-N,2-dimethylpropanamideHCID 16063536—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-de68df9420224a10bc2a476204700e3f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)