Water → 2-chloro-N-isopropyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

HRID 189184Notes

Reaction equation

HRID 189184 reaction equation
[CH3:18][CH:19]([CH3:20])[NH2:21].[CH3:23][N:24]1[CH2:25][CH2:26][CH2:27][C:28]1=[O:29].[Cl:1][c:2]1[n:3][c:4]([Cl:17])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[CH2:9][CH2:10]2.[OH2:22]>>[Cl:1][c:2]1[n:3][c:4]([NH:21][CH:19]([CH3:18])[CH3:20])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[CH2:9][CH2:10]2

Participants

5

Reactant 4

HCID 962WaterHCID 6363IsopropylamineHCID 13387N-methyl-2-pyrrolidoneHCID 580754632,4-Dichloro-7-phenyl-6,7-dihydro-5H-cyclopenta[D]pyrimidine

Product 1

HCID 580754032-chloro-N-isopropyl-7-phenyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-c7a29124e7c8454fbc331cdbb67608d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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