反应详情

Dichlorodiphenoxymethane (2 g, 7.46 mmol) and methylsulfonamide (1.56 g, 16.41 mmol) were dissolved in EtOAc (15 ml) and heated to reflux for 12 hours. The mixture was allowed to cool and was concentrated under vacuum. Purification of the crude mixture by flash chromatography (20% EtOAc/hexanes) afforded diphenyl methylsulfonylcarbonimidate (0.75 g, 2.59 mmol, 35%).

1. temperatureheated
2. temperatureto reflux for 12 hours
3. temperatureto cool
4. concentrationwas concentrated under vacuum
5. customPurification of the crude mixture by flash chromatography (20% EtOAc/hexanes)