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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1892292Generated: October 30, 2026

Hydrazine hydrate (1:1) → tert-Butyl 4-(aminooxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/1892292

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantTert-butyl 4-(1,3-dioxoisoindolin-2-yloxy)piperidine-1-carboxylateHCID 21751544—
Producttert-Butyl 4-(aminooxy)piperidine-1-carboxylateHCID 2472948285%

Reaction Steps

The title compound was prepared from tert-butyl 4-(1,3-dioxoisoindolin-2-yloxy)piperidine-1-carboxylate and hydrazine monohydrate in 85% yield using the same procedure as described in the synthesis of intermediate G

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08507676B2
Source datasetuspto-grants-2013_08
ORD IDord-ebc95ac13ed64307a27bbdc49a3cc3da
Source noteuspto-grants-2013_08