Hydrazine hydrate (1:1) → HCID 39247809, compound

HRID 1892294Notes

Reaction equation

HRID 1892294 reaction equation
O=C1C2C(=CC=CC=2)C(=O)[N:3]1[O:12][CH2:13][CH:14]1[CH2:19][CH2:18][N:17]([C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:16][CH2:15]1.O.NN>>[NH2:3][O:12][CH2:13][CH:14]1[CH2:19][CH2:18][N:17]([C:20]([O:22][C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21751545HCID 21751545, compound

Product 1

HCID 39247809HCID 39247809, compoundYield 85%

Procedure

The title compound was prepared from t-butyl 4-((1,3-dioxoisoindolin-2-yloxy)methyl)-piperidine-1-carboxylate and hydrazine monohydrate in 85% yield using the same procedure as described in the synthesis of intermediate B.

Sources & evidence

ORD record
ord-0bcd369c36474cb696708224e9e7e0f9
Source dataset
uspto-grants-2013_08
Patent number
US08507676B2

Reaction notes

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