HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-Hydroxyphthalimide → Methyl ((1,3-dioxo-1,3-dihydro-2H-isoindol-2-YL)oxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Product | Methyl ((1,3-dioxo-1,3-dihydro-2H-isoindol-2-YL)oxy)acetate | HCID 748410 | 56% |
Reaction Steps
The title compound was prepared from 2-hydroxyisoindoline-1,3-dione and methyl 2-bromoacetate in 56% yield using the same procedure as described in the synthesis of intermediate G. LCMS (method B): [MH]+=236, tR=1.82 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507676B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-5411b31f73aa497db2eeff1b38d7d0ed |
| Source note | uspto-grants-2013_08 |