HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-iodobenzoate → Ethyl 4-(cyclobutyl(hydroxy)methyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-iodobenzoate | HCID 142891 | — |
| Reactant | Cyclobutanecarbaldehyde | HCID 12431621 | — |
| Product | Ethyl 4-(cyclobutyl(hydroxy)methyl)benzoate | HCID 68157714 | — |
Reaction Steps
The title compound was prepared by a method analogous to that described for Intermediate (16), using ethyl 4-iodobenzoate and cyclobutanecarbaldehyde. 1H NMR (400 MHz, CDCl3, δ): 7.93 (d, J=8.0 Hz, 2H), 7.31 (d, J=8.0 Hz, 2H), 4.58 (d, J=8.0 Hz, 1H), 4.29 (q, J=6.8 Hz, 2H), 2.50-2.58 (m, 1H), 1.70-2.02 (m, 6H), 1.34 (t, J=7.2 Hz, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507533B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-85da38dc6f9e4adebeef67b4c23df2c2 |
| Source note | uspto-grants-2013_08 |