Bicarbonate Ion → 4-{3-chloro-4-[(1-methyl-1H-imidazole-2-yl)sulfanyl]anilino}-6-methoxy-7-{2-[4-(1-pyrrolidinyl)-1-piperidinyl]ethoxy}-3-quinolinecarbonitrile
Reaction equation
[C:45](=[O:46])([OH:47])[O-:48].[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:32][CH3:33])[cH:7][c:8]2[c:9]([NH:17][c:18]3[cH:19][c:20]([Cl:31])[c:21]([S:24][c:25]4[n:26]([CH3:30])[cH:27][cH:28][n:29]4)[cH:22][cH:23]3)[c:10]([C:15]#[N:16])[cH:11][n:12][c:13]2[cH:14]1.[N:34]1([CH:39]2[CH2:40][CH2:41][NH:42][CH2:43][CH2:44]2)[CH2:35][CH2:36][CH2:37][CH2:38]1.[Na+:49]>>[CH2:2]([CH2:3][O:4][c:5]1[c:6]([O:32][CH3:33])[cH:7][c:8]2[c:9]([NH:17][c:18]3[cH:19][c:20]([Cl:31])[c:21]([S:24][c:25]4[n:26]([CH3:30])[cH:27][cH:28][n:29]4)[cH:22][cH:23]3)[c:10]([C:15]#[N:16])[cH:11][n:12][c:13]2[cH:14]1)[N:42]1[CH2:41][CH2:40][CH:39]([N:34]2[CH2:35][CH2:36][CH2:37][CH2:38]2)[CH2:44][CH2:43]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cfefe499e2744150bfb716ab6299487c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…