Thiophene-3-carboxylic acid → HCID 66934843, compound
Reaction equation
O1C=[CH:4][C:3]([C:6](O)=O)=[CH:2]1.[S:9]1[CH:13]=[CH:12][C:11]([C:14]([OH:16])=[O:15])=[CH:10]1>>[C:14]([C:13]1[S:9][CH:10]=[C:11]([C:14]([O:16][C:3]([CH3:2])([CH3:4])[CH3:6])=[O:15])[CH:12]=1)(=[O:15])[CH2:11][CH3:10]Participants
3
Procedure
Instead of the starting material compound of Reference Example 104, that is, 3-furan carboxylic acid, 3-thiophencarboxylic acid was used for the similar procedure as in Reference Example 104 to obtain tert-butyl 5-propionyl-3-thiophencarboxylate.
Sources & evidence
- ORD record
- ord-8de5ce426adb4cf381af5a941a3a6b98
- Source dataset
- uspto-grants-2013_08
- Patent number
- US08507714B2
Reaction notes
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