HRID1892860

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID519683

2-Methyl-5-nitrobenzoic acid

C8H7NO4

HCID7016560

4-nitro-1H-pyrrole-2-carboxylic Acid

C5H4N2O4

结构：CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1c[nH]c(C(=O)O)c1

HCID57671144

未命名化合物

PRODUCTS

生成物

结构：CC[C@@H](NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1ccc(C)c(C(=O)O)c1

HCID57671059

未命名化合物

PROCEDURE

实验过程

Instead of the starting material compound of Example 262, that is, the 4-nitropyrrole-2-carboxylic acid, 2-methyl-5-nitrobenzoic acid was used for the similar procedure as in Example 262 to obtain the title compound.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-660400dd4bcf42b9a7137eaae868612e
来源数据集: uspto-grants-2013_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08507714B2
来源说明: uspto-grants-2013_08

反应 SMILES

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:35][CH3:36])=[C:6]([CH:34]=1)[CH2:7][CH:8]1[C:14](=[O:15])[N:13]([C:16]([NH:18][C@H:19]([CH2:31][CH3:32])[C:20]([NH:22][C:23]2[CH:24]=[C:25]([C:28]([OH:30])=[O:29])N[CH:27]=2)=[O:21])=[O:17])[CH2:12][C:11](=[O:33])[NH:10][CH2:9]1.[N+]([C:40]1[CH:41]=C(C(O)=O)N[CH:44]=1)([O-])=O.CC1C=CC([N+]([O-])=O)=CC=1C(O)=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:35][CH3:36])=[C:6]([CH:34]=1)[CH2:7][CH:8]1[C:14](=[O:15])[N:13]([C:16]([NH:18][C@H:19]([CH2:31][CH3:32])[C:20]([NH:22][C:23]2[CH:27]=[CH:44][C:40]([CH3:41])=[C:25]([CH:24]=2)[C:28]([OH:30])=[O:29])=[O:21])=[O:17])[CH2:12][C:11](=[O:33])[NH:10][CH2:9]1