HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methyl-5-nitrobenzoic acid → 5-{[(2R)-2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino-}-2-methylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methyl-5-nitrobenzoic acid | HCID 519683 | — |
| Reactant | 4-nitro-1H-pyrrole-2-carboxylic Acid | HCID 7016560 | — |
| Reactant | 4-{[(2r)-2-({[6-(5-Chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino}-1h-pyrrole-2-carboxylic acid | HCID 57671144 | — |
| Product | 5-{[(2R)-2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino-}-2-methylbenzoic acid | HCID 57671059 | — |
Reaction Steps
Instead of the starting material compound of Example 262, that is, the 4-nitropyrrole-2-carboxylic acid, 2-methyl-5-nitrobenzoic acid was used for the similar procedure as in Example 262 to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08507714B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-660400dd4bcf42b9a7137eaae868612e |
| Source note | uspto-grants-2013_08 |