反应详情

温度

70 °C

43.2 g of 2,3-diphenylbenzo[b]furan, 31.3 g of N-bromosuccinimide, and 400 mL of N,N-dimethylformamide were loaded into a flask, and the mixture was stirred under heat at 70° C. for 8 hours. After having been cooled to room temperature, the reaction solution was poured into 2 L of water. The precipitated crystal was separated by filtration, washed with methanol, water, and methanol in the stated order, and purified by silica gel column chromatography, whereby 40.2 g of a pale yellow crystal were obtained (72% yield).

1. temperatureAfter having been cooled to room temperature
2. customThe precipitated crystal was separated by filtration
3. washwashed with methanol, water, and methanol in the stated order
4. custompurified by silica gel column chromatography