HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → Acetic acid 3-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-vinyl-tetrahydro-furan-2-yl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | (6-Benzyloxy-2,2-dimethyl-5-vinyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-diphenyl-silane | HCID 67360139 | — |
| Product | Acetic acid 3-acetoxy-4-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-5-vinyl-tetrahydro-furan-2-yl ester | HCID 131730809 | 85% |
Reaction Steps
A flask was charged with (6-Benzyloxy-2,2-dimethyl-5-vinyl-tetrahydro-furo[2,3-d][1,3]dioxol-5-ylmethoxy)-tert-butyl-diphenyl-silane, Acetic acid, acetic acid anhydride, and H2SO4. The reaction was stirred, extracted, and the solvent was evaporated to provide the titled compound in 85% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513214B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-6202bd376f074e4db2347946b0153ca5 |
| Source note | uspto-grants-2013_08 |