HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenol → HCID 4496358, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenol | HCID 996 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Ethyl 2-bromopropionate | HCID 79040 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 4496358 | HCID 4496358 | 103% |
Reaction Steps
Phenol (24.28 g, 0.25 mol), potassium carbonate (39.2 g 0.28 mol), and ethyl 2-bromoproionate (46.7 g, 0.25 mol) were combined in acetone (200 mL) and stirred at room temperature over night. The acetone was removed in vacuo, the residue was purified in silica to provide a golden oil (50 g, 90%), Rf=0.80 in 10:1 ethyl acetate: petroleum ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513233B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-efd50d613ba943d4adb190a5f76069cc |
| Source note | uspto-grants-2013_08 |