HCID 12134925, compound → Ethyl 3-(4-hydroxyphenyl)-2-methyl-2-phenoxypropionate

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Reaction Steps

2-Phenoxy-3-(4-benzyloxyphenyl)-2-methyl-propionic acid ethyl ester (24.1 g, 59.3 mmol) was dissolved in ethanol (200 mL) and treated with 10% palladium on carbon (2.41 g), and then stirred under an atmosphere of hydrogen for 20 h. The suspension was filtered through celite and concentrated in vacuo to produce 3-(4-hydroxyphenyl)-2-methyl-2-phenoxypropionic acid ethyl ester colorless oil (16.9 g, 95%).

Provenance & Evidence