Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1893238Generated: November 3, 2026

1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → HCID 49763806, compound

https://huagongshe.com/reaction/1893238

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 15908—
Reactant((3-(Trifluoromethyl)benzoyl)amino)acetic acidHCID 2777432—
ReactantHCID 86646679HCID 86646679—
ProductHCID 49763806HCID 49763806—

Reaction Steps

The title compound was prepared as a white solid from an EDCI coupling of 1-[4-(4-amino-phenyl)-cyclohexyl]-azetidin-3-ylamine TFA salt (as prepared in the previous step) and (3-trifluoromethyl-benzoylamino)-acetic acid using the procedure described in Step F of Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08513229B2
Source datasetuspto-grants-2013_08
ORD IDord-079d5046ac8443fdb3526e53c148060d
Source noteuspto-grants-2013_08