HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 15023907, compound → HCID 49764574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 15023907 | HCID 15023907 | — |
| Reactant | N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide | HCID 59361594 | — |
| Product | HCID 49764574 | HCID 49764574 | — |
Reaction Steps
The title compound was prepared as a white solid by reductive amination of 4-(1-hydroxy-4-oxo-cyclohexyl)-benzoic acid methyl ester (as prepared in Example 9, Step B) and N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide (as prepared in step B of Example 4) using the procedure described in Step C of Example 4 followed by base catalyzed hydrolysis of the ester using the procedure described in Example 10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08513229B2 |
| Source dataset | uspto-grants-2013_08 |
| ORD ID | ord-88427252e5284ce2a406bb6866033156 |
| Source note | uspto-grants-2013_08 |